EFFECTS OF PROPOLIS ON BREAST CANCER CELLS

Evaluation of Turkish propolis for its chemical composition, antioxidant capacity, anti-proliferative effect on several human breast cancer cell lines and proliferative effect on fibroblasts and mouse mesenchymal stem cell line

Ozdal et al. (2018) reported that Turkish propolis is rich in flavonoids of pinocembrin, chrysin, galangin, pinobanksin, pinostrobin, and phenolic acids of caffeic acid, p-coumaric acid, ferulic acid, and t-cinnamic acid. In this scientific study, anti-proliferative and proliferative effects of propolis extracts were also investigated on two different breast cancer cell lines; MDA-MB-231, UACC-3199, and two standard cell lines; fibroblasts and mouse mesenchymal stem cell lines. According to the results, the Turkish propolis showed a significant anti-proliferative effect on MDA-MB-231 and UACC breast cancer cell lines. The scientists reported a proliferative effect on both fibroblasts and mouse mesenchymal stem cells of Turkish propolis. It was suggested that Turkish propolis be considered a potent agent for breast cancer treatment.* *Ozdal T et al., 2018. Evaluation of Turkish propolis for its chemical composition, antioxidant capacity, the anti-proliferative effect on several human breast cancer cell lines, and proliferative effect on fibroblasts and mouse mesenchymal stem cell line. Journal of Apicultural Research, 57(5), pp.627-638.

Source:  https://www.tandfonline.com/doi/abs/10.1080/00218839.2018.1494888