BEE&YOU Apibeauty Anti-aging gezichtsserum
BEE&YOU Anti-rimpel en anti-aging gezichtsserum is voornamelijk samengesteld met bijengif, hyaluronzuur, propolis-extract, rauwe honing, plantenextracten, glycerine en aqua. Bevat geen chemicaliën.
Wat is bijengif?
Bijengif is een complex mengsel van eiwitten en aminozuren, enzymen, suikers en lipiden. Melittine, een polypeptide, is een belangrijk bestanddeel van gif en bij mensen stimuleert het de bijnierschors (een deel van de bijnier) om cortisol af te geven, een hormoon dat wordt geassocieerd met het verminderen van ontstekingen en genezingsreacties. Bijengif wordt veel gebruikt als cosmetisch ingrediënt (actueel middel) voor het bevorderen van huidregeneratie of een behandeling van bepaalde epidermale aandoeningen. Topische toepassing van bijengif kan goed worden verdragen door de menselijke huid omdat het in wetenschappelijke studies geen potentieel voor huidirritatie heeft vertoond. Langdurige behandeling met bijengif bevattende cosmetica is veilig omdat het irritatiepotentieel van bijengif verwaarloosbaar is.
SKU: 152NLDKAYS
BEE&YOU Anti-Wrinkle & Anti-aging Face Serum is mainly formulated with bee venom, hyaluronic acid, propolis extract, raw honey, plant extracts, glycerin and aqua. Contains no chemicals.
Main Purpose of Use and Benefits:
POWERFUL 100% NATURAL FORMULA: Deeply penetrates within skin's surface and helps replenish dry skin, for radiant, younger-looking skin with Aqua, Glycerin, Raw Honey, Iris Florentina Root Extract, Myrtle Tree Leaves Extract, Laurel Leaf Extract, Kiwifruit Extract, Corn Starch, Beet Root Extract, Rosa Multiflora Fruit Extract, Hydroxyethyl cellulose, Hyaluronic Acid, Propolis Extract, Bee Venom.
REDUCES FINE LINES AND WRINKLES: While improving skin’s texture and radiance, reduces fine lines and wrinkles. In 1 week, visibly plumps for younger looking skin that feels firmer, more elastic, and radiant; Skin looks and feels dewy instantly and overtime.
MINIMIZE PORES & IMPROVES ELASTICITY:Minimizes pores over time for smoother skin & deep moisturizing. Improves the elasticity & tonicity of your skin and assists with firming and revitalizing your skin
SOOTHES INFLAMED SKIN & BLEMISHES: Bee Venom helps to nourish, plump and firm the skin. Soothes inflamed skin while helping to heal blemishes along with bee propolis extract.
SUITABLE FOR EVERY SKIN TYPE: dry skin, oily skin, combination skin, sensitive skin, and mature skin.
Directions: Apply gently with your fingertips in the morning and in the night, with circular movements. Use with Anti-aging Eye Contour Serum and Anti-aging Face Cream for effective care of the whole face.
The above-listed effects were observed by healthy volunteers aged 33-70 who used this product for three weeks in a dermatological panel test. No irritation or allergenic reaction was observed by 15 volunteers, over 30 years old with sensitive skin, who used the products for three weeks in a dermatological patch test.
Yeditepe University (YÜ – AGAM, Istanbul, Turkey) carried out both tests.Main Purpose of Use and Benefits:
POWERFUL 100% NATURAL FORMULA: Deeply penetrates within skin's surface and helps replenish dry skin, for radiant, younger-looking skin with Aqua, Glycerin, Raw Honey, Iris Florentina Root Extract, Myrtle Tree Leaves Extract, Laurel Leaf Extract, Kiwifruit Extract, Corn Starch, Beet Root Extract, Rosa Multiflora Fruit Extract, Hydroxyethyl cellulose, Hyaluronic Acid, Propolis Extract, Bee Venom.
REDUCES FINE LINES AND WRINKLES: While improving skin’s texture and radiance, reduces fine lines and wrinkles. In 1 week, visibly plumps for younger looking skin that feels firmer, more elastic, and radiant; Skin looks and feels dewy instantly and overtime.
MINIMIZE PORES & IMPROVES ELASTICITY: Minimizes pores over time for smoother skin & deep moisturizing. Improves the elasticity & tonicity of your skin and assists with firming and revitalizing your skin.
SOOTHES INFLAMED SKIN & BLEMISHES: Bee Venom helps to nourish, plump and firm the skin. Soothes inflamed skin while helping to heal blemishes along with bee propolis extract.
SUITABLE FOR EVERY SKIN TYPE: dry skin, oily skin, combination skin, sensitive skin, and mature skin.
Applications of Bee Venom in Skin Care
Shrinks Pores: Bee venom is the best solution for pores. Its astringent properties help in removing excess oil and fluid from both the pores of skin and its uppermost layers.
Relieves Inflammation: One of the most important benefits of Bee Venom is its powerful anti-inflammatory effects. The soothing Adolapin which bee venom houses, it can quickly reduce the burning, redness, and swelling on skin.
Minimizes Wrinkles: Bee venom is known for its wrinkle-eliminating properties. It helps in stimulating blood flow inside body which makes the blood easier to flow to the surface of the skin. This ease of blood flow stimulates both the collagen and elastin production. Aside from this, what’s unique about Bee Venom is its ability to strengthen tissues to be able to stop premature aging.
Fades Blemishes: Bee venom properties which smooth are wrinkles & frown lines and shrink pores are also the ones who help fade acne blemishes. It also contains a peptide known as Melittin. Melittin has anti-bacterial and antimicrobial effects which are useful in fighting against acne.
Relaxes Muscles: The Bee Venom is helpful in relaxing the muscles as it strengths collagen and elastin to remain taut.
Directions: Apply gently with your fingertips in the morning and in the night, with circular movements. Use with Anti-aging Eye Contour Serum and Anti-aging Face Cream for effective care of the whole face.
| Major Compounds of Bee Venom | Description |
|---|---|
| Melittin | It is the main component of Bee Venom which is a 26- residue peptide, accounting 40-60% of Venom’s composition. The peptide has carboxyl- terminal region which is hydrophilic in nature & is responsible for lytic action. The amino- terminal region is hydrophobic in nature with no lytic activity. |
| Apamin | It is an 18- amino acid peptide which contains two disulfide bridges. Apamin is the smallest neurotoxin in the Bee Venom. It constitutes about 2-3% dry weight of Bee Venom. |
| Adolapin | It is a polypeptide with 103 amino acids residue. It constitutes about 1% dry weight of Bee Venom. |
| Mast-Cell Degranulating (MCD) Peptide | The MCD peptide is also known as Peptide 401, which is a Bee Venom Polypeptide containing 22 amino acids which is similar to apamin structure where both of them contains two disulfide bonds. It constitutes about 2-3% dry weight of Bee Venom. The mast cell degranulating peptide echoes the biological action in histamine release from mast cells. |
| Phospholipase A2 (PLA2) | PLA2 is single polypeptide chain of about 128 amino acids containing about four sulfide bridges. It is the most fatal enzyme in the Bee Venom. Bee Venom PLA2 is about 12-15% of Bee Venom’s dry weight & very alkaline in nature. |
| Hyaluronidase | Hyaluronidase is responsible to break down hyaluronic acid in tissues. It allows the active component of Bee Venom to effectively diffuse into the victim’s tissue, responsible to affect the structural integrity and thereby increase the blood flow in that area. These actions combine together & increase the spreading of venom. It constitutes about 1.5-2% of dry weight of Bee Venom. |
| Ingredient Description | Benefits |
|---|---|
| Water | Moisturizer. |
| Natural compound derived from vegetable oils | Moisturizer. |
| Natural honeybee product | Antimicrobial, good for acne-prone ski, moisturizes the skin. |
| Extract of the roots of the Orris | Inhibits the activity of enzymes causing the breakdown of proteins in the extracellular matrix (collagen and elastin) and favours the synthesis of DEJ (dermal-epidermal junction) anchor proteins. It reinforces the skin barrier and decreases the depth of wrinkles. |
| Evergreen shrub extract native to the Mediterranian region | Increases cellular longevity and limit glycation. By limiting glycation, hydrolyzed Myrtus communis leaf extract helps the skin to maintain its strength and elasticity, resulting in a more youthful appearance. |
| Extract of the leaves of the Laurel | Antiseptic, antibacterial, and anti-fungal. Good for acne, inflamed skin and dandruff, but is also effective for healing of minor wounds. |
| Natural absorbant corn starch | Moisturizes the skin. |
| Beet Root Extract | Skin conditioning. |
| Extract of the fruit of Rosa multiflora | Masking, and tonic. |
| Natural gelling and thickening agent derived from cellulose | Improves the texture and feel of the formulations. |
| Natural humectant | Makes skin plumper, dewier and more hydrated, reduces the appearance of fine lines and wrinkles, speeds up wound healing. |
| Extract of resin bee propolis | Antioxidant and antimicrobial, good for acne-prone skin, reduces appereance of wrinkles and smooth out skin, recudes redness related to acne, allergies etc. |
| Natural complex mixture of proteins and amino acids, enzymes, and lipids | powerful anti-inflammatory and increases blood circulation, gently plumping out and firming the skin, filling and smoothing fine lines and wrinkles. |
What is Bee Venom?
Bee Venom is a complex mixture of proteins and amino acids, enzymes, sugars, and lipids. Melittin, a polypeptide is a major component of venom, and in humans it has the effect of stimulating the adrenal cortex (part of the adrenal gland) to release cortisol, a hormone associated with reducing inflammations and healing responses. Bee venom has been widely used as a cosmetic ingredient (topical agent) for promoting skin regeneration or a treatment of certain epidermal conditions. Topical application of bee venom can be well tolerated in the human skin because it has exhibited no dermal irritation potential in scientific studies. Long-term treatment with bee venom-containing cosmetics is safe because the irritation potential of bee venom is negligible.
Physical Properties of Bee Venom
Color: Transparent liquid, dried venom color is light yellow or brown. This is because oxidation of some of the proteins of venom.
Odor: Odorless, or honey like
Smell: Ornamental pungent
PH: 4.4-5.5
Clinical Studies
Vitiligo: It is an abnormal pigmentation which is characterized by depigmentation of skin and hair. This is because of melanocyte proliferation, melanogenesis, and migration or increases in dendricity. As reported by Jeon et al., bee venom treatment elevates the melanocyte proliferation about two times as compared to the control in 1 week. By application of bee venom, the expression of MITF-M protein increases to the maximum level on third day and slowly decreases till fifth day. Bee venom treatment increases the ratio of cells with more than two dendrites by 23% in a time-dependent manner. The results showed that by bee venom treatment, the number of migrated cells as compared to the controls increases. It also induced melanocyte dendricity and melanocyte migration. The in-vitro study of bee venom has a positive effect on melanocyte proliferation, melanogenesis, dendricity, and migration. Thus, for treatment of vitiligo by repigmenting the skin, bee venom can be useful.
Facial Wrinkles: The beneficial effects of serum containing bee venom on facial wrinkles was studied by several scientific research where the application of bee venom serum resulted in decreased average wrinkle depth, total wrinkle area and count. It was also reported that the topical application of bee venom is safe for human use. Studies that were conducted on animals showed that it was well tolerated by them, and no dermal irritation was seen. Thus, application of bee venom is effective in improving the skin wrinkles thereby increasing the production of collagen and elastin.
Acne: As reported by Han et al. they performed a randomized double blind control trail where the therapeutic effects of bee venom on acne was examined. Subjective evaluation was done where bee venom on acne was applied by skin care products which contain bee venom and products which do not contain bee venom for a period of 2 weeks. The results showed that the subjects that were applied cosmetics containing bee venom relatively showed a reduction by 57.5% in ATP levels, by the count of inflammatory & non-inflammatory lesions compared to the control, thereby measuring a decrease in the count of microbes. Therefore, Han et al. suggested that cosmetic containing bee venom is a good component as a therapeutic agent for acne.
Atopic Dermatitis: It is a type of skin disorder usually characterized by a defective skin barrier, drying of the skin, pruritus, eczema and by some allergic responses. It is a chronic, inflammatory skin disorder which may worsen if not treated properly. Bee Venom, because of its anti-inflammatory mechanism, it can be useful for atopic dermatitis. As reported by You et al. they did evaluation of about 136 subjects which were random distribution in different groups. Some subjects were applied bee venom containing moisturizer and silk protein and moisturizer without bee venom for a period of 4 weeks. The results indicate that application of the moisturizer with bee venom showed significantly lower eczema area and severity index and visual analogue scale, value compared to the patients who applied moisturizer without bee venom. There were as such no outstanding differences in the incidence of side effects induced by bee venom on the subject’s skin.
Applications of Bee Venom in Skin Care
Shrinks Pores: Bee venom is the best solution for pores. Its astringent properties help in removing excess oil and fluid from both the pores of skin and its uppermost layers.
Relieves Inflammation: One of the most important benefits of Bee Venom is its powerful anti-inflammatory effects. The soothing Adolapin which is bee venom houses, it can quickly reduce the burning, redness, and swelling on skin.
Minimizes Wrinkles: Bee venom is known for its wrinkle-eliminating properties. It helps in stimulating blood flow inside the body which makes the blood easier to flow to the surface of the skin. This ease of blood flow stimulates both collagen and elastin production. Aside from this, what’s unique about Bee Venom is its ability to strengthen tissues to be able to stop premature aging.
Fades Blemishes: Bee venom properties which smooth are wrinkles & frown lines and shrink pores are also the ones who help fade acne blemishes. It also contains a peptide known as Melittin. Melittin has anti-bacterial and antimicrobial effects which are useful in fighting against acne.
Relaxes Muscles: The Bee Venom is helpful in relaxing the muscles as it strengths collagen and elastin to remain taut.
Who we are?
Woman Entrepreneur and Food Scientist Dr Asli Samanci needed to find a solution to her son’s weakened immune system. A Pediatrician recommended that she try giving her son propolis. She started production of propolis for the first time for her son and subsequently developed a patented propolis extraction method. Based on this experience, she founded BEE&YOU to help those who want to support their immune system naturally.
Woman Entrepreneur and Food Scientist Dr Asli Samanci needed to find a solution to her son’s weakened immune system. A Pediatrician recommended that she try giving her son propolis. She started production of propolis for the first time for her son and subsequently developed a patented propolis extraction method. Based on this experience, she founded BEE&YOU to help those who want to support their immune system naturally. Our products are produced by our “Contracted Beekeeping” model to assure the highest quality, and traceability from our hives to your table. Our products are also tested for their purity, antibacterial activity, antioxidant activity and compliance with food safety standards. Our facility is GMP (according to Code of Federal Regulations Title 21 Part120 FDA and Part111 FDA), BRC (Global Standard for Food Safety), IFS Food, ISO 22000:2018 (Food Safety Management System), ISO 9001:2015 (Quality Management System), OU Kosher and Halal Certified. Our latest accredited third-party (by DQS CFS GmbH in Germany) audit IFS Food score is 98.06 over 100. We support beekeeping and beekeepers! Help save the Bees and Nature! Each time you buy a product, certain amount goes directly to beekeepers to help improve their business
How do we produce our products?
This product is produced by our “Contracted Beekeeping” model to assure the highest quality, and traceability from our hives to your table. Our products are also tested for their purity, antibacterial activity, antioxidant activity and compliance with food safety standards. Our facility is GMP (according to Code of Federal Regulations Title 21 Part120 FDA and Part111 FDA), BRC (Global Standard for Food Safety), IFS Food, ISO 22000:2018 (Food Safety Management System), ISO 9001:2015 (Quality Management System), OU Kosher and Halal Certified. Our latest accredited third-party (by DQS CFS GmbH in Germany) audit IFS Food score is 98.06 over 100. We support beekeeping and beekeepers! Help save the Bees and Nature! Each time you buy a product, certain amount goes directly to beekeepers to help improve their business.
What is Anatolian Bee Propolis?
Propolis is a natural bee product that honeybees collect from the leaves, buds and stems of the plants. Honeybees use propolis to protect their beehive from fungus, bacteria, and viruses. It acts as a natural protective barrier. We source our propolis from pristine Anatolian mountains which are home to 12,000 different plant species and one of the most biodiverse regions in the world. BEE&YOU has a patented extraction technology which enables us to extract all biologically active compounds (phenolics, flavonoids, minerals, vitamins, enzymes) of propolis to make bioavailable for our body. Mainly 2 things completely differ our propolis quality from any other propolis on the market; the region where we source our propolis (Anatolian region rich in 12,000 different plant species) and our patented extraction technology. Our propolis has minimum x3 more of phenolic, flavonoid and antioxidant content than any other propolis and Manuka Honey on the market. Our propolis has at least 80 times greater antioxidant content than pomegranate juice! Anatolian propolis extract contains a minimum of 15 different phenolic and flavonoid compounds and each of them has different health benefits!
WHY BEE&YOU PRODUCTS ?
Extraction & Team of Experts: BEE&YOU has patented extraction technology and founders have more than 50 years of academic and industrial experience. Therefore, our propolis has x3 more antioxidants than other propolis and x100 than manuka honey.
Award-winning bee products: Our bee products, made with an award-winning and patented extraction process, have earned over 50 international awards.
Contracted Beekeeping: Faire Trade and Sustainable production to ensure that the products are pesticide free, chemical free, heavy metal free and 100% Traceable
Area: Our beehives are placed at the pristine Anatolian mountains which are home to 12,000 different plant species. These plants create the special nectar, resin, pollen, and water which the bees feed from. These special properties are what make our propolis, raw honey, bee pollen and royal jelly so exceptional and healthy.
Real Story: Founding story of BEE&YOU (desperate mother produces these miracle products for his son’s low immunity problem) provides a strong emotional tie with our customers.
We love bees and nature: Help Save the Bees and Nature! Each time you buy a product, a certain amount goes to beekeepers as beekeeping equipment and beehives to support their business.
BEE&YOU products are Gluten-Free, Non-GMO, No Artificial Flavors, No Added Sugar, No Preservatives. Our products are also tested for their purity, antioxidant activity, antibacterial activity, and compliance with FDA and CODEX regulations.
BEE&YOU Facility is periodically audited by third party accredited organizations such as BRC, IFS, ISO and the last audit score is 98.06 out of 100. BEE&YOU is GMP, BRC, IFS, Kosher, Halal, ISO 9001:2015, ISO 22000:2018 and HACCP certified.
Clinical Studies
Vitiligo: It is an abnormal pigmentation which is characterized by depigmentation of skin and hair. This is because of melanocyte proliferation, melanogenesis, and migration or increases in dendricity. As reported by Jeon et al., bee venom treatment elevates the melanocyte proliferation about two times as compared to the control in 1 week. By application of bee venom, the expression of MITF-M protein increases to the maximum level on third day and slowly decreases till fifth day. Bee venom treatment increases the ratio of cells with more than two dendrites by 23% in a time-dependent manner. The results showed that by bee venom treatment, the number of migrated cells as compared to the controls increases. It also induced melanocyte dendricity and melanocyte migration. The in-vitro study of bee venom has a positive effect on melanocyte proliferation, melanogenesis, dendricity, and migration. Thus, for treatment of vitiligo by repigmenting the skin, bee venom can be useful.
Facial Wrinkles: The beneficial effects of serum containing bee venom on facial wrinkles was studied by several scientific research where the application of bee venom serum resulted in decreased average wrinkle depth, total wrinkle area and count. It was also reported that the topical application of bee venom is safe for human use. Studies that were conducted on animals showed that it was well tolerated by them, and no dermal irritation was seen. Thus, application of bee venom is effective in improving the skin wrinkles thereby increasing the production of collagen and elastin.
Acne: As reported by Han et al. they performed a randomized double blind control trail where the therapeutic effects of bee venom on acne was examined. Subjective evaluation was done where bee venom on acne was applied by skin care products which contain bee venom and products which do not contain bee venom for a period of 2 weeks. The results showed that the subjects that were applied cosmetics containing bee venom relatively showed a reduction by 57.5% in ATP levels, by the count of inflammatory & non-inflammatory lesions compared to the control, thereby measuring a decrease in the count of microbes. Therefore, Han et al. suggested that cosmetic containing bee venom is a good component as a therapeutic agent for acne.
Atopic Dermatitis: It is a type of skin disorder usually characterized by a defective skin barrier, drying of the skin, pruritus, eczema and by some allergic responses. It is a chronic, inflammatory skin disorder which may worsen if not treated properly. Bee Venom, because of its anti-inflammatory mechanism, it can be useful for atopic dermatitis. As reported by You et al. they did evaluation of about 136 subjects which were random distribution in different groups. Some subjects were applied bee venom containing moisturizer and silk protein and moisturizer without bee venom for a period of 4 weeks. The results indicate that application of the moisturizer with bee venom showed significantly lower eczema area and severity index and visual analogue scale, value compared to the patients who applied moisturizer without bee venom. There were as such no outstanding differences in the incidence of side effects induced by bee venom on the subject’s skin.
Wat te verwachten?
